Chitra Karki
Senior Director, Liver/Inflammatory Diseases, Global Evidence and Outcomes Takeda Pharmaceutical
Chitra Karki is a Senior Director at Takeda and an experienced global evidence and outcomes leader with deep expertise in real‑world evidence (RWE) and health economics and outcomes research (HEOR). She has extensive experience supporting assets from early development through commercialization, with a focus on translating clinical, economic, and patient-centered data into compelling value for regulators, payers, and healthcare providers. Chitra has led observational and epidemiologic studies, comparative effectiveness research, and outcomes strategy across multiple therapeutic areas, with a strong track record in communicating evidence to drive informed decision-making.
Seminars
This interactive workshop brings together leaders across epidemiology, biostatistics, HEOR, and market access to examine where RWE breaks down in practice, and how to design evidence that consistently delivers decision impact.
This workshop will gather experts to discuss:
- Identifying where RWE fails to translate into regulatory, payer, and clinical decisions despite strong methodology
- Understanding how different stakeholders interpret uncertainty, bias and evidence strength, and why alignment breaks down even with high-quality data
- Balancing data complexity with clarity by ensuring analytical approaches, including advanced methods and AI, remaining interpretable and decision‑relevant
- Applying statistical and epidemiological rigor to improve comparability, mitigate bias, and ensure outputs are credible across use cases
- Designing evidence strategies earlier in development that align with downstream
decision needs to reduce rework, delays, and missed impact
